CAUSES OF INFERTILITY DUE TO ENDOMETRIOSIS: PROSTAGLANDINS
Prostaglandins are substances that are produced by many tissues throughout the body, including endometrial implants. One of their functions is to control the contraction and relaxation of the muscles in many of the internal organs of the body including the uterus and fallopian tubes.
It is thought that women with endometriosis have higher concentrations of prostaglandins in their peritoneal fluid and that these higher concentrations may contribute to infertility by hindering or preventing conception and implantation in a number of ways.
It is possible that prostaglandins interfere with the functioning of the ovaries and prevent the release of the ovum thereby preventing fertilisation.
Prostaglandins help the ovum move along the fallopian tube.
If the fertilised ovum is propelled too rapidly along the tube the ovum will reach the uterus too quickly. Therefore, when the fertilised ovum reaches the uterus it may not be mature enough to implant itself in the endometrium or the endometrium may not be ready to accept the fertilised ovum. If the fertilised ovum is propelled too slowly down the fallopian tube it may not reach the uterus in time to embed itself in the endometrium.
Prostaglandins may also affect the relaxation and contraction of the uterus. If they produce excessive contractions of the uterus they may prevent implantation of the fertilised ovum or they may cause it to be expelled soon after implantation.
*91\83\2*
Random Posts
Categories: Women's Health |
